Top INDEX
• Basics: Enhancement.
• About : beta-Hydroxybutyric acid.
• Health: Uses of beta-Hydroxybutyric acid.
• Article: Benefits of Beta Hydroxybutyrate.
• Article: The Dysbiotic toxin accumulation.
• Article: Dysbiosis Symptoms & Treatment.
• Article: What Is A Beta Hydroxybutyrate Test?
• Article: Detox 101: How to Enhance Your Body’s Detoxification.

  Product Possibilities, NOT Recommendations.

  Product: Instaketones Powder, Julian Bakery.

  Product: KetoActiv, Sun Force.

  Product: KetoForce - Exogenous ... beta-hydroxybutrate (BHB).

• Insight: Ketoacidosis.
• Insight: The Relevancy of Diagnosis before Treatment.
• Comment: Don't miss the Sabotaging Key.

• Definitions.
• -Focus-: Monographs on Toxins and Enhancers.

Basics: Enhancement. INDEX
https://en.wikipedia.org/wiki/Beta-Hydroxybutyric_acid
LINK 2:https://well.ca/products/julian-bakery-instaketones-powder_137362.html
LINK 3:

The compound can be used as an energy source by the brain when blood glucose is low.

ß-Hydroxybutyric acid is able to cross the blood-brain-barrier into the central nervous system.
Levels of ß-hydroxybutyric acid increase in the liver, heart, muscle, brain, and other tissues with

exercise, 
calorie restriction, 
fasting, and 
ketogenic diets. 

Ketones are a super fuel that can be efficiently used by the muscles and the brain,
where they generate more energy (ATP) per unit of oxygen consumed than do carbohydrates, protein, or fat.

About: beta-Hydroxybutyric acid. INDEX
https://en.wikipedia.org/wiki/Beta-Hydroxybutyric_acid

ß-Hydroxybutyric acid, also known as 3-hydroxybutyric acid, is an organic compound ...

In humans, D-3-hydroxybutyrate is synthesized in the liver from acetoacetate, the first ketone produced in the fasting state.

The biosynthesis is catalyzed by the enzyme beta-hydroxybutyrate dehydrogenase.

beta-hydroxybutyrate's concentration, as with other ketone bodies, is raised in ketosis.
This elevated beta-hydroxybutyrate level is naturally expected, as beta-hydroxybutyrate is formed from acetoacetate.
The compound can be used as an energy source by the brain when blood glucose is low.

Diabetic patients can have their ketone levels tested via urine or blood to indicate diabetic ketoacidosis.

In alcoholic ketoacidosis, this ketone body is produced in greatest concentration.

In epilepsy patients on the ketogenic diet, blood ß-hydroxybutyrate levels correlate best with degree of seizure control.

Ketogenesis occurs if oxaloacetate in the liver cells is depleted, a circumstance created by reduced carbohydrate intake (through diet or starvation), prolonged, excessive alcohol consumption, and/or insulin deficiency. Because oxaloacetate is crucial for entry of Acetyl-CoA into the TCA cycle, the rapid production of Acetyl-CoA from fatty acid oxidation in the absence of ample oxaloacetate overwhelms the decreased capacity of the TCA cycle, and the resultant excess of Acetyl-CoA is shunted towards ketone body production.

Health: Uses of beta-Hydroxybutyric acid. INDEX
https://en.wikipedia.org/wiki/Beta-Hydroxybutyric_acid

ß-Hydroxybutyric acid is able to cross the blood-brain-barrier into the central nervous system.
Levels of ß-hydroxybutyric acid increase in the liver, heart, muscle, brain, and other tissues with

exercise, 
calorie restriction, 
fasting, and 
ketogenic diets. 

The compound has been found to act as a histone deacetylase (HDAC) inhibitor.
Through inhibition of the HDAC class I isoenzymes HDAC2 and HDAC3, ß-hydroxybutyric acid has been found to increase brain-derived neurotrophic factor (BDNF) levels and TrkB signaling in the hippocampus.

... ß-hydroxybutyric acid mediates the effects of exercise on BDNF levels in the hippocampus.
... may have clinical relevance in the treatment of depression, anxiety, and cognitive impairment.

Article: Benefits of Beta Hydroxybutyrate. INDEX
https://www.nootropedia.com/beta-hydroxybutyrate/

There are a host of benefits of beta hydroxybutyrate, but it is primarily known as a fuel source in the absence of glucose.
Within 24 – 72 hours without food, the body no longer uses glucose as the main fuel support system, which is when ketones like beta hydroxybutyrate kick into production. Fasting as long as 382 days (with medical supervision) is possible purely because of ketone production.

Evidence suggests that beta hydroxybutyrate can increase the level of brain-derived neurotrophic factor (BDNF) in the hippocampus, which is the main memory center of the brain. This is some of the only published literature about the performance enhancing effects of beta hydroxybutyrate, though there are several self-experiments.

Namely, Dr. Peter Attia (popularized by Tim Ferriss’ podcast and Attia’s blog) has concluded there are benefits of reduced oxygen consumption by the brain. These statements have been confirmed to some degree by Dr. Dom D’Agostino when describing under-water oxygen utilization and ketones, but neither are well-researched.

Most of the evidence regarding beta hydroxybutyrate utilizes this exogenous ketone as a way to recovery from memory damage or impairment or as a neuroprotective agent.

In one 2004 study of memory-impaired adults, beta hydroxybutyrate successfully aided in improving memory recall.
For Alzheimer’s patients, using beta hydroxybutyrate is particularly helpful as a neuroprotective agent.

Many of the long-term and neuroprotective benefits of beta hydroxybutyrate are closely linked to reduced carbohydrate and glucose consumption as well. For those who are consuming both exogenous ketones and eating glucose, the benefits are known.

The benefits of beta hydroxybutyrate are not only for people who are currently experiencing nutritional ketosis. Often it is possible for athletes to utilize ketone bodies as a fuel source to limit glycogen depletion

Side Effects of Beta Hydroxybutyrate
There are few known side effects of beta hydroxybutyrate when consumed in the recommended dosage ranges.
Because this is a naturally produced compound in the human body (and brain), it is relatively well tolerated.
In order to supply the compound via supplementation, many products include sodium, calcium, and potassium salts.

Beta Hydroxybutyrate Dosage
The standard dosage of beta hydroxybutyrate is 10 – 12 grams per serving.
Dosage is important when using beta hydroxybutyrate.

One potential side effect of beta hydroxybutyrate is overdosing and death at high ranges.
The toxicity range in animals is quite high, but it is best to stay within the recommended range of beta hydroxybutyrate.

It may also be useful for people using nutritional ketosis to incorporate blood glucose and ketone testing into their regimen.

This is from Dr. Peter Attia and is a warning for anyone interested in trying the unflavored option:

“The ketone esters are, hands-down, the worst tasting compounds I have ever put in my body. The world’s worst scotch tastes like spring water compared to these things…It tasted as I imagine jet fuel would taste. I thought I was going to go blind. I didn’t stop gagging for 10 minutes …”

Article: The Dysbiotic toxin accumulation. INDEX
https://www.diagnose-me.com/symptoms-of/bacterial-dysbiosis.php

Bacterial Dysbiosis: Overview
LINK 2: 5 Tell Tale Signs of Dysbiosis and Leaky Gut.
http://www.leakygutcure.com/blog/symptoms/dysbiosis-leaky-gut/

LINK 3: Dysbiosis: Microbial Imbalance Inside the Body.
https://www.doctorshealthpress.com/health-articles/dysbiosis-microbial-imbalance/
By Jon Yaneff, CNP - April 4, 2016

LINK 4: Dysbiosis Decoded: Symptoms, Why You Get It, and Link to Autoimmunity,
Breast Cancer, Irritable Bowel Syndrome, Plus Other Common Conditions
By Sara Gottfried MD
http://www.saragottfriedmd.com/dysbiosis-symptoms-and-conditions/

Approximately 500 species of bacteria, as well as many species of yeast and other organisms, live in the human gastrointestinal tract and make up the "gut flora." These “friendly” bacteria are vital for good digestion and the health of the intestines in general, and mostly have names beginning with “Lactobacillus” or “Bifidobacteria,” which denotes the class of bacteria they belong to. ...

When the gut flora is in a healthy balance it is called "orthobiosis," which is a term introduced in the early 1900s by the great microbiologist Elie Metchnikoff. When our gut is out of balance we are said to have "dysbiosis." Metchnikoff thought dysbiosis so concerning that he coined the expression "Death begins in the GUT!"

Dysbiosis is an imbalance in your gut flora caused by too few beneficial bacteria and an overgrowth of bad bacteria, yeast, and/or parasites. The more clinical term that relates to the problem is “Small Intestinal Bacterial Overgrowth” (SIBO), and this term refers to the gut flora that crawled backward into the small intestine from the colon, where it belongs.

In general, your gut flora, called the microbiota, and their DNA, called your microbiome, are stable in healthy people. But a shift in the microbiota can lead to a permanent imbalance known as dysbiosis. Frankly, I don’t know many people with normal microbiota and microbiome. Maybe three people in the past 10 years, and it’s becoming alarmingly rare.

Your intestinal microbiota are inherited at birth from your mother as you move through the vaginal canal (or not).
Later, your diet and lifestyle become more important in their effect on the structure of your microbiota and their diversity.
Overall, your microbiota consist of approximately 1014 microbes, which outnumber human cells by 10-fold, and perform several key functions:

• synthesizing vitamin K and other essential nutrients,
• preventing your gut wall from becoming leaky,
• digestion of cellulose,
• promoting angiogenesis,
• supporting enteric nerve function,
• keeping your immune system healthy and recognizing self versus nonself,
• preventing kidney stones,

Illness can occur when the amount of friendly bacteria is reduced and the other organisms are able to increase their numbers and become the majority. There are a number of factors that can disrupt the balance of organisms in the intestines and lead to overgrowth of the less desirable species. The most important factors are:

• Antibiotic misuse,
• Mercury dental amalgams
• Heavy metals in foods, air, soil, water.
• Destructive parasite infestation,
• Toxic chemical use/presence in workplace or home,
• Use of the birth control pill (for longer periods than 2 years),
• Use of other hormones, especially immunosuppressants like steroids
• Diet, especially one high in (refined) sugar and/or carbs,
• Alcohol, "recreational" drugs,
• Stress (unplanned for and unprepared for dramatic changes)

Conditions often caused by dysbiosis include Irritable Bowel Syndrome, acne, food allergies, Chronic Fatigue and depression. But you can help repopulate the good bacteria by eating foods that contain natural, healthy bacterias, including yogurt and acidophilus milk. You also can take an acidophilus supplement and something called Fructo-oligosaccharides (FOS), which is a plant-based supplement that serves as a “super food” for these good bacteria.

Gut dysbiosis can lead to changes in the lining of the bowel that increases the permeability of the intestine, resulting in leaky gut syndrome.

Article: Dysbiosis Symptoms & Treatment. INDEX
https://www.diagnose-me.com/symptoms-of/bacterial-dysbiosis.php

Bacterial Dysbiosis: Overview
LINK 2: 5 Tell Tale Signs of Dysbiosis and Leaky Gut.
http://www.leakygutcure.com/blog/symptoms/dysbiosis-leaky-gut/

LINK 3: Dysbiosis: Microbial Imbalance Inside the Body.
https://www.doctorshealthpress.com/health-articles/dysbiosis-microbial-imbalance/
By Jon Yaneff, CNP - April 4, 2016

LINK 4: Dysbiosis Decoded: Symptoms, Why You Get It, and Link to Autoimmunity,
Breast Cancer, Irritable Bowel Syndrome, Plus Other Common Conditions
By Sara Gottfried MD
http://www.saragottfriedmd.com/dysbiosis-symptoms-and-conditions/

... The symptoms of dysbiosis are vague and often go unnoticed, undiagnosed, and even worse, dismissed by your conventional health care clinicians. It is estimated that over 30 million people in the U.S, predominantly women, suffer from the multiple effects of an imbalance in the gastrointestinal system.

... the gastrointestinal tract or the digestive system – is often underrated.
But it plays a huge part in your health and well being. When you are not digesting food properly, all kinds of problems can arise: nutrients may not be ingested leading to low energy levels; your immune system can become compromised, leading to viral and bacterial infections; other bodily systems can be affected from the skin to your nervous system; and lastly poor digestion can lead to toxic bacteria infesting your intestinal tract, a condition called gut dysbiosis. Digestion usually becomes compromised by the medical system itself, improper eating, hormones, psychology, and lifestyle habits.

There is no one symptom indicator, but, if you have 5 or more of the below symptoms, there is a good chance you have dysbiosis.

• Psoriasis,
• Chronic bad breath,
• Fatigue or low energy,
• Food sensitivities,
• Cramping, urgency,
• Heartburn,
• Autoimmunity,
• Hashimoto’s thyroiditis,
• Foul smelling stools,
• Rectal or vagina itching,
• Weak or cracked fingernails,
• Iron deficiency,
• Weight Loss or Gain,
• Loss of libido and infertility,
• Sugar cravings, including alcohol,
• Brain fog, anxiety, or depression,
• Mucus in your poop once per week,
• Bladder problems like interstitial cystitis,
• Frequent gas or bloating on most days of the week,
• Loose stool, diarrhea, constipation, or a combination,
• Diagnosis of Irritable Bowel Syndrome (IBS),
• History of “stomach bugs,” gastroenteritis, and/or food poisoning,
• Use of anti-acids for heartburn, reflux, or hiatal hernia,
• Carbohydrate intolerance, particularly after eating fiber and/or beans,
• History of prolonged antibiotics such as for acne or sinusitis,
• Multiple sclerosis,
• Sinus congestion

The Relevancy of Diagnosis before Treatment.
Like Chronic Fatigue Syndrome, CFS-ME, Dysbiosis is a term that loosely connects a number of separate, yet combined influence illness factors. Part of the difficulty in diagnosing and effective treatment of this syndrome or package of illnesses is that the awareness and perception of most health care providers has been educated to expect and look for a singular problem with a simple and dramatic solution. This is neither. The importance of determining the presence or absence of dysbiosis in the current diagnosis is advocated as a means of utilizing ß-Hydroxybutyric acid in a relevant manner. If dysbiosis is NOT a concern, the benefits of the use of ß-Hydroxybutyric acid can be realized. If dysbiosis is a concern and reality, the use of ß-Hydroxybutyric acid may not only fail to be effective in improving and maintaining health ... it may even make the situation worse.

The Dysbiotic Pattern Lifestyle can include these:

• breast cancer,
• colorectal cancer,
• irritable bowel syndrome, autoimmunity,
• obesity,
• diabetes,
• gestational diabetes ,
• autism,
• Parkinson’s disease,
• poor detoxification of endocrine disruptors or xenobiotics,
• chronic venous insufficiency,

Candida and dysbiosis can also spread through sexual intercourse.
That is why both partners should be treated when dysbiosis, candida, or other bacterial infection is suspected.
Also, healing dysbiosis is very individual and what may work for one person may not work for another.

Testing.
The most useful diagnostic test for dysbiosis is called a comprehensive digestive stool analysis (CDSA).

The CDSA will include a number of procedures such as biochemical evaluations of digestion, evaluation of bacterial microflora, detection of abnormal mycology, evaluation of intestinal absorption, and the detection of metabolic markers of intestinal metabolism.

From these tests, excessive triglycerides, meat, vegetable fibers, fatty acids, or cholesterol may indicate gut dysbiosis. Severe dysbiosis cases may also result in abnormal blood tests that indicate low levels of vitamin B12 and folic acid, and malabsorption of proteins.

Other tests used for dysbiosis include the breath hydrogen test, candida testing, the Genova IP test for leaky gut, u-biome tests to offer a bigger picture of the bacteria in the body, and zonulin testing. Zonulin is a protein that is commonly implicated in leaky gut syndrome and levels will often be high.

Some Treatment Possibilities.

1. Herbal therapy:
   There are many useful herbs in a natural dysbiosis treatment.
   Some of these herbal remedies include
   • oregano oil,
   • garlic,
   • goldenseal
   • berberine,
   • wormwood or Chinese wormwood;
   • grapefruit seed extract,
   • thyme,
   • cat’s claw,
   • tea tree oil,
   • peppermint,
   • pau d’arco,
   • Echinacea,
   • fennel,
   • amalaki reishi mushroom,
   • olive leaf,
   • cinnamon,
   • myrrh,
   • turmeric,
   • burdock
   • bearberry,
   • elecampane,
   • Oregon grape,
   • kelp,
   • calendula.
   
   

2. Essential oils:
   A study published in the journal Alternative Medicine Review in 2009 found that the most promising essential oils for dysbiosis include
   • caraway,
   • lavender,
   • ajwain,
   • bitter orange,
   • sweet fennel,
   • star anise,
   • peppermint.
   
   

3. Homeopathic remedies:
   There are various homeopathic remedies used to benefit the digestive system.
   For instance, candida albicans is a homeopathic preparation that is useful when candida overgrowth is a contributing factor to gut dysbiosis. Other remedies recommended for inflammation of the gastrointestinal tract include
   • cantharis,
   • aresnicum album,
   • colocynthis,
   • carbo vegetabilis,
   • nux vomica,
   • china, and
   • pulsatilla.

Article: What Is A Beta Hydroxybutyrate Test? INDEX
http://www.medicalhealthtests.com/beta-hydroxybutyrate.html
Submitted on March 27, 2012

Preparation
A test for any ketone body is nearly always done in a case of a medical emergency and therefore negates the possibility of any kind of preparation. It is however important that the doctor is informed whether the patient has consumed any alcohol.

Normal and Abnormal Beta Hydroxybutyrate Levels
Keeping a constant check on the beta hydroxybutyrate levels helps doctors to treat patients of diabetes faster and more accurately.
People who develop diabetes could be admitted to hospital with ketoacidosis.
By checking the beta hydroxybutyrate levels; the doctors can monitor the condition.

Treatment for abnormal beta hydroxybutyrate levels includes introducing artificial insulin into the body to prevent the condition from occurring. Testing to see if a person has normal beta hydroxybutyrate levels helps to check the effectiveness of insulin supplements as well. The normal beta hydroxybutyrate levels in serum are less than 3 mg/dl while the normal beta hydroxybutyrate levels in blood are between 0.21 to 2.8 mg/dl.

Anything above these levels is considered elevated or abnormal beta hydroxybutyrate levels.
The other main reasons for high or abnormal beta hydroxybutyrate levels are starvation, continuous vomiting or any other digestive problem which results in the food not being properly absorbed into the body.

During starvation, the body produces ketones to help with the breakdown of fat metabolism.
Elevated beta hydroxybutyrate levels may also occur when an individual in on a diet that is low in carbohydrates.
This is one of the causes of high beta hydroxybutyrate levels but is not harmful for the body.

The beta hydroxybutyrate range can be measured by simple blood test.
Low beta hydroxybutyrate levels or abnormal beta hydroxybutyrate levels should be reported to the doctor immediately so that treatment can be started.

Test Benefits:
Checking for beta hydroxybutyrate level is done by performing a beta hydroxybutyrate test or more specifically, a beta hydroxybutyrate assay. This is a test that would be conducted on a blood sample. There are convenient kits that are available for this and can even be purchased on the internet.

The test is conducted to find the levels of the ketone body, which, if elevated, indicates the possibility of ketoacidosis taking place. In most cases, when a patient is suspected of suffering from diabetic shock, the patient's breath is the most potent method of guessing if there is ketoacidosis. The patient's breath would smell like nail polish remover. This is because of the presence of acetone. The patient must then be prescribed the assay to distinguish between diabetic ketoacidosis or alcoholic ketoacidosis.

Ketoacidosis is a condition where the body has insufficient insulin and is therefore not able to absorb blood sugar.
The body has already produced ketones to help breakdown the fats to produce energy. A combination of high blood sugar and the accumulation of ketones in the blood is dangerous and can be life threatening.

Article: Detox 101: How to Enhance Your Body’s Detoxification. INDEX
https://justinhealth.com/enhance-body-detoxification/
Dr. Justin Marchegiani, D.C. -- Just In Health Wellness Clinic.
February 16th, 2015 -- (512) 535-1817

Looking at blood can be helpful, but it’s not the best functional indicator.
Organic acids testing tends to be the best indicator when looking at the functions of detoxification, and then appropriate actions can be taken based on the results.

Anytime we are trying to detoxify, we want to stop putting toxins into our body.
Eat organic foods, drink plenty of water, sleep well, and manage stress and blood sugar.

To eliminate or minimize stress on the body, make diet and lifestyle changes and address gut stressors and infections.
It’s important to address infections because they will throw off the bacteria in the gut. If bacteria in the gut is off, it will create backup in the small and large intestines, which increases toxins and creates that vicious cycle. ...

Blood Tests
In conventional medicine we have our typical blood tests -- CBC or CMP.
Within these we look at the following specific tests:

    ALT: Liver specific
    AST: Heart and skeletal muscle specific
    GGT: Gallbladder and bile duct specific

The ALT tends to be more focused to the liver, but it’s a more general marker.

The AST is also a liver marker, but there are various isoenzymes that can be broken down from this test.
AST levels may increase during an acute episode of a heart attack or a hard CrossFit workout.
However, if they are chronically high, it’s a good sign there are detoxification issues or liver problems.

The problem with the ALT and AST is chronic elevation in these blood tests doesn’t usually happen until late in the game.
Full liver function is 100%; when it drops down to 10–20%, that’s when we’ll see the elevated tests.
They are a late-stage indicator in the game of toxicity.

The GGT is a good marker for gallbladder issues, and it will elevate when something is going on in the gallbladder.

When the ALT, AST, or GGT goes above 20 or so, that’s when we will want to take a closer look and find what’s causing the elevation.

Urinary Organic Acid Test
Simple urinary tests can provide an assessment of organic acids in the body.
The organic acids test includes the following:

    2 Methyl hippurate
    Glucorate
    Oratate
    A-Hydroxybutyrate
    Pyroglutamate
    Sulfate

These tests tend to be a little more significant because they are specific to different nutrients.
If we’re looking at acetylation or sulfation, we look at the results of sulfer-based amino acids.
Glucorate and 2 methyl hippurate can be more specific to B vitamins.

So organic acids give us really good indicators of what pathways aren’t working properly.
Then we can put people on specific supplement programs to help up-regulate pathways that are low or out of balance.

Toxins In Your Fat
Many people may gain stubborn weight that no matter what they do they just can’t lose it.
Most toxins are fat soluble so the body has a propensity to shuttle toxins into these fat cells.
The body will then be more resistant to burning up this toxin-filled fat until it has the capacity to do so.

In other words, if you have a detoxification system that is not operating at optimal function, excessive weight gain could be a side effect. Once the body’s phase 1 and phase 2 detoxification pathways are supported, the body finally has the ability to tap into these isolated fat cells!

I see this toxin-derived weight gain in my patients from time to time.
Also lets not forgot that over 20% of thyroid hormone is activated in the liver.
If the liver is under more stress, it makes sense that your thyroid function or thyroid hormones may not be at optimal levels to burn fat.

Your thyroid is one the master glands that controls metabolism.
Metabolism is how your body creates energy…ideally from fat.
The less metabolic energy you have, the harder it will be to tap into that stubborn fat.

Detox, Protein, and Amino Acids
Protein is vital for detoxification to occur.
Some of the main antioxidants that help with detoxification include glutathione and superoxide dismutase.
Glutathione is a big one and is made up of three protein-based amino acids: cystine, glutamine, and glycine.

We need amino acids to run our detox pathways.
Our body then eliminates these toxins, primarily via the stool and the urine. So it’s very important our gut function is working properly. ...

Detox and the Gut
The gallbladder is a small green organ just beneath the liver.
After toxins enter the liver, the liver produces bile, and this bile concentrates in the gallbladder.
The gallbladder spits bile into the intestinal tract, and the bile is eliminated from the body via the stool.

If the gut’s not working properly because we have dysbiosis or are chronically constipated, autointoxication, a process that slows down the activity in the small and large intestines, will occur. This creates more toxicity that will have to go through the whole detoxification process again.

This additional toxicity occurs because of the slowed activity and a bacteria in our gut called beta-glucoronidase.
We conjugate bile, which means our body binds it into a toxin or a hormone so it can be eliminated.
If the bacteria in our gut is out of balance, beta-glucoronidase can take those bound-up, or conjugated, toxins and uncleave, or unbind, them. So gut function is really important in detoxifying the body.

We don’t want dysbiosis.
We want higher good bacteria and lower bad bacteria.
Unfortunately, most people have higher bad bacteria and lower good bacteria.

Product: Instaketones Powder Orange Burst, Julian Bakery. INDEX
https://well.ca/products/julian-bakery-instaketones-powder_137362.html
Regular: $119.99 --- Special: $107.99 --- Caffeine Free 525g --- 30 servings

How often is it that we see a truly new product in the supplement industry?
Most are simply rehashes of supplements we have all seen before.
InstaKetones is a novel and innovative product born out of ketogenic research.

InstaKetones is a source of ketones, which act as the fuel your body uses and prefers when you go into a ketogenic state.
And now you don’t have to be in a ketogenic state to benefit from the power of ketones.
InstaKetones is a readily available source of this amazing fuel.

Ketone bodies (ketones) are energy sources that are produced and burned under special metabolic conditions such as starvation and high fat consumption (ketogenic diets).

Ketones are a super fuel that can be efficiently used by the muscles and the brain, where they generate more energy (ATP) per unit of oxygen consumed than do carbohydrates, protein, or fat.

InstaKetones contains 11.7 grams of the ketone body Beta-Hydroxybutyrate (BHB) per serving (Max amount of Ketones the Human Body can uptake per Serving) in a delicious orange flavored base. It contains no artificial sweeteners, flavorings or colors. Consuming InstaKetones before exercise can result in significant increases in oxygen demand and performance. InstaKetones may also heighten mental acuity and performance.

InstaKetones is excellent for ketogenic dieters who need energy but must limit carbohydrate intake.
InstaKetones may also be used by individuals who consume carbohydrates to provide an additional energy source, and limit exercise-induced glycogen depletion. It may also be used to ease the transition into a ketogenic state. It may help alleviate the fatigue and lethargy some experience while making the transition from a glucose-dominant to a ketone metabolism.

For best results, InstaKetones should be stirred vigorously into 8 ounces of cold water until dissolved.

InstaKetones can be combined with pure Caprylic Acid
(From MCT Oil) for an even greater effect.

Features:
• 11.7 g BHB Per Scoop (Measurable Blood Ketones In 45 Min Or Less)
• (60 Servings Total 30 w/Caffeine & 30 Without
• Burn Stored Fat As Energy + Infused w/ Organic Caffeine 100mg & One Non-Caffeine Bag

Benefits:
• Curing Hangovers,
• Mental Clarity,
• Orange Tart Taste (Kind Of Salty)
• IKDiet Compliant
• Easy To Mix
• 60 Servings Total)
• 1.16 lbs of Caffeine & 1.16 Non-Caffeine

Ingredients:

Beta Hydroxybutyrate,
Amino Acid Blend,
-- (L-Taurine, L-Tyrosine, L-Luecine), Calcium, Sodium,
Citric Acid, Orange Extract, Lou Han Guo Extract (Monk Fruit).

Product: KetoActiv, Sun Force. INDEX
http://www.oliverhealthfoods.ca/
Product # 04001, 150 gm, 30 servings -- Black Cherry Almond flavor
Retail: $119.99 --- Special: $109.00
2017-10-18: Product is new in the store by one week.

Helps in Energy Metabolism.
Also promotes brain metabolism and improved focusing, curbs cravings, reduces oxidative damage, burns more fat easier.

• MCT Free
• Low Sodium
• 1000 mg Butyric acid per scoop
• --- 40 mg Green tea extract per scoop
• 2040 mg Betahydroxybutyrate per scoop
• 124 mg Potassium per scoop
• Citric acid
• Malic Acid
• Beet Powder
• Inulin
• Stevia
• Silicon Dioxide
• electrolytes

Helps assist individuals into KETOSIS by reducing the natural struggle of the body as it adapts to low-carb eating styles.
This "struggle" is due to the body adjusting to using Ketosis as an alternative to glucose food source and is often referred to as "the Keto flu."

Use to boost exercise performance

Ingredients: per measure
     1000 mg -- Butyric acid 
       40 mg -- Green Tea extract 
 2040,816 mg -- Beta-Hydroxybut 
   123.75 mg -- Potassium 

Product: KetoForce - Exogenous ketone body beta-hydroxybutrate (BHB). INDEX
https://www.ergomaxsupplements.com/
prototype-nutrition-keto-force-beta-hydroxybutrate-480-ml
Founded in 2007 by Dutch brothers Samuel and Paul Zonneveld
Ergomax, PO Box 6831, 6503GH Nijmegen, Netherlands
English: +3124-6635366 -- info@ergomax.nl
Fast & secure delivery within Europe
Regular: EUR 79.95 -- Special Price EUR 75.95 (2017-12) -- 480 ml

• Exogenous keto-ester
• Directly in ketosis
• Beta-hydroxybutyrate (BHB)
• Sugar Free Energy Drink
• For (endurance) athletes and professionals
• Ketoforce

KetoForce contains the endogenous ketone body beta-hydroxybutrate (BHB) in sodium and potassium salt form.
Ingestion of KetoForce will raise the levels of blood ketones (BHB and AcAc) for 2.5-3.0 hours after ingestion.
When taken an hour before exercise this product has been shown to decrease the amount of oxygen consumed at a given power output.

Suggested Use:
It is suggested that this product be consumed during the initial stages of a ketogenic diet (three times a day for first 2-3 days) to accelerate ketosis and ease metabolic transition. It can be consumed once a day once ketosis has been achieved for help with ketosis maintenance. The product may also be consumed prior to high intensity aerobic exercise to enhance performance, especially for those on a low carb/ketogenic diet.

This product has an alkaline pH 10-11 so it is best mixed with an acidic beverage
(i.e. diet lemonade, grapefruit juice, etc) prior to ingestion.

One bottle contains 480 mL or approximately (16) 30 cc servings.
This product can be used up to three times per day.

Dosage: 3 cups.

Ingredients per serving:
0 grams fat, 1,6 grams natrium, 11.7 grams beta-hydroxybutyrate, 1,6 grams potassium.

Other ingredients:
Sodium, beta-hydroxybutyrate, potassium, water, citric acid, sodium hydroxide.

DEFINITIONS.

angiogenesis
Angiogenesis is the growth of blood vessels from the existing vasculature.
It occurs throughout life in both health and disease, beginning in utero and continuing on through old age.
No metabolically active tissue in the body is more than a few hundred micrometers from a blood capillary, which is formed by the process of angiogenesis. Capillaries are needed in all tissues for diffusion exchange of nutrients and metabolites. Changes in metabolic activity lead to proportional changes in angiogenesis and, hence, proportional changes in capillarity. Oxygen plays a pivotal role in this regulation. Hemodynamic factors are critical for survival of vascular networks and for structural adaptations of vessel walls.

... Stimulation of angiogenesis can be therapeutic in ischemic heart disease, peripheral arterial disease, and wound healing.
Decreasing or inhibiting angiogenesis can be therapeutic in cancer, ophthalmic conditions, rheumatoid arthritis, and other diseases. Capillaries grow and regress in healthy tissues according to functional demands. Exercise stimulates angiogenesis in skeletal muscle and heart. A lack of exercise leads to capillary regression. Capillaries grow in adipose tissue during weight gain and regress during weight loss. ...
beta-glucoronidase
An enzyme found in lysosomes. It is involved in the breakdown of glycosaminoglycan.
... has been implicated in estrogen metabolism and cell division; it occurs in the spleen, liver, and endocrine glands; deficiency results in Sly's syndrome.

Sly syndrome.
Deficiencies in ß-glucuronidase result in the non recessive inherited metabolic disease known as Sly syndrome or Mucopolysaccharidosis VII. A deficiency in this enzyme results in the build-up of non-hydrolyzed mucopolysaccharides in the patient. This disease can be extremely debilitating for the patient or can result in hydrops fetalis prior to birth. In addition, mental retardation, short stature, coarse facial features, spinal abnormalities, and enlargement of liver and spleen are observed in surviving patients.

dysbiosis
Dysbiosis is a term for a microbial imbalance that most often affects a person’s digestive tract.
... dysbiosis can also affect the skin, eyes, lungs, ears, nose, sinuses, nails, and vagina.

Dysbiosis is also sometimes called dysbacteriosis or bacterial dysbiosis.
That is because the gastrointestinal tract (GI tract) contains both “good” and “bad” bacteria to form the gut flora -- also called the gut microbe.

glycosaminoglycan
A family of carbohydrates that help with the maintenance and support of collagen and elastin.
Glycosaminoglycans' primary role is to maintain and support collagen, elastin and turgidity (bounce) in the cellular spaces and keep protein fibers in balance and proportion. It also promotes the ability of the collagen and elastin fibers to retain moisture, therefore remaining soluble. In skin care products, they are essential to the epidermal & dermal cells metabolism and keeping the collagen and elastin of the skin in good condition. GAGs are important in the reaction of copper peptides to help repair wrinkles and scarring. Known as the water reserve of the viable epidermis and dermis, these carbohydrates are dependent on fluid intake. Glycosaminoglycans are also linked to the lymphatic system.

Some examples of Glycosaminoglycan's natural uses in the body include heparin as an anticoagulant, hyaluronate as a component in the synovial fluid lubricant in body joints, and chondroitins which can be found in connective tissues, cartilage and tendons

orthobiosis
Right living; a term used by E. E. Metchnikoff in the early 1900s to encompass all the factors that may affect longevity and well-being.

A body that feels at home, whose feelingnature is free of conflict and fixation, and is at ease in an everchanging world is a body integrated in gravity. Élie Metchnikoff, the father of immunology, coined the word “orthobiosis” to describe the everongoing striving of life to improve upon and enhance itself and its circumstances.

Concentrating on the role of health care professionals, ... communication is crucial in developing health consciousness in modern societies. The argumentation leads to the notion of orthobiosis, which expresses the idea of a modern health-conscious democratic community.

INDEX