Health Optimization Power Tools

Serrapeptase, or, Serratiopeptidase.

A proteolytic enzyme,
with antibiofilm property.


Revised: March 12, 2013

 

INDEX




Introduction.
Adapted from "Inflammation, Disease, and Serrapeptase"
The Whole Foods Market E-Newsletter & E-Savings
organictrina@shaw.ca

The prime cause of western diseases is now considered to be chronic inflammation caused by eating starchy carbohydrates, processed, micro-waved and generally overcooked foods. This is measured by the rise in C-Reactive proteins after eating such foods. When we have chronic inflammation as well as free radical damage, we get what is known as sticky blood, where the platelets stick together and can clot.

Serrapeptase has had wide clinical use - spanning over twenty-five years throughout Europe and Asia - as a viable alternative to salicylates, ibuprofen and the more potent NSAIDs. Unlike these drugs, Serrapeptase is a naturally occurring, physiological agent with no inhibitory effects on prostaglandins and is devoid of gastrointestinal side effects.

Serrapeptase is a proteolytic enzyme isolated from the micro-organism Serratia E15. This enzyme is naturally processed commercially today through fermentation and was discovered in the silkworm intestine. This immunologically active enzyme is completely bound to the alpha 2 macroglobulin in biological fluids. Histological studies reveal powerful anti-inflammatory effects of this naturally occurring enzyme.

Serrapeptase digests non-living tissue, blood clots, cysts, and arterial plaque and inflammation in all forms. The late German physician, Dr. Hans Nieper, used Serrapeptase to treat arterial blockage in his coronary patients. Serrapeptase protects against stroke and is reportedly more effective and quicker than EDTA Chelation treatments in removing arterial plaque. He also reports that Serrapeptase dissolves blood clots and causes varicose veins to shrink or diminish. ...




Enzymes to limit Viruses.
Adapted from " Fighting Viruses, and Winning"
http://life-enthusiast.com/index/Concerns/Influenza/...
by Dr William Wong

... Viruses cannot be beat by using herbs, colostrum, or any of the popular multi-level marketing products touted as being immune enhancers and germ fighters. The nastier viruses will not succumb to extremes in body temperature either fever or cold. In short, viruses are perfect weapons because they can't easily be done away with. ...

Many doctors now believe that Chronic Fatigue Syndrome and Fibromyalgia are nothing more than Post Polio Syndrome in those who received the live cell (mildly active strain) polio oral inoculation instead of the dead (chopped to pieces) Salk vaccine!

Pointing to the correlation between the brain swelling and 30 some odd common symptoms that occur in Polio, Post Polio Syndrome, and Chronic Fatigue Syndrome, the English medical establishment calls Chronic Fatigue "Myalgia Encephalitis" (muscle pain with brain swelling) to denote the connection of these three diseases. Here in the States the liability issues for doctors, governments and drug companies are too great for anyone in the medical establishment here to admit a connection between the live virus vaccine and the later onset of debilitating disease. ...

.. the US Office of Naval Research has agreed with me. .. following ... protein eating (proteolytic) enzymes. Yep, the same things that control your digestion also clean your laundry and are your body's first line of defense in:

    • Fighting Inflammation. (1)
    • Eating Fibrosis and scar tissue. (2)
    • Modulating Immune Function. (3)
    • Cleaning the Blood, (4)
    • Enzymes can also be the first line of defense against a virus!

... proteolytic enzymes (eat) the all-important exterior protein coating of the virus. .. the virus is active as long as its coating is intact. What happens when a virus cannot complete an Isoprin bond? Well, it simply becomes inert - harmless!

... Formulating an enzyme preparation with a combination of protein eating enzymes, he then applied the concoction to the control of various conditions and reducing viral load was one of them. (5,6). Systemic (or body wide) enzymes are best selling products in Europe and Asia. They work so well for the four actions mentioned above that everyone from little old ladies with osteo or rheumatoid arthritis take it as well as every pro and Olympic team there.

In research against viruses, systemic enzymes have been found to greatly reduce the viral load by rendering the virus inert. The trick to having enzymes work is to take enough of them. Some 5 to 10 tablets 3 times a day! ...

    SUMMARY:
  1. Salt (increases Alkalinity).
  2. Calcium and magnesium supplements.
  3. Avoid vaccines, negative stress, people.
  4. Oxygen: K0-7 from Aerobic Life Industries, in Phoenix.
  5. Enzymes that are protein eating (proteolytic) , fastest & strongest
    Vitalzym, from Phoenix, Arizona. OR
    Zymitol
    http://life-enthusiast.com/index/Brands/GenPlus/Product:_Zymitol



NOTE:
Vitalzym is a serrapeptase extra strength systemic enzyme supplement. ..

      Serrapeptase Vitalzym can help:
    • Fibromyalgia - Arthritis - Chronic Joint Pain (serrapeptase)
    • Chronic Fatigue
    • Chronic Pain – Inflammation
    • Clogged Arteries – Fibroids
    • Spider Veins – Viral Infection
    • Circulatory disorders
    • Systemic Yeast Infection
    • Autoimmune Diseases
    • Post-Operate Scarring
    • Fibrocystic Breast Disease (serrapeptase)
    • Bladder Infections

In the body, proteolytic digestive enzymes are produced in the pancreas, but supplemental forms of enzymes may come from fungal or bacterial sources, extraction from the pancreas of livestock animals (trypsin/chymotrypsin) or extraction from plants (such as papain from the papaya and Bromelain from pineapples). The primary uses of proteolytic enzymes in dietary supplements are used as digestive enzymes, anti-inflammatory agents and pain relievers. There are a number of clinical trials showing the benefit of using oral proteolytic enzymes as a digestive aid. Proteolytic enzymes are also theorized to help reduce symptoms of food allergies and as a treatment for rheumatoid arthritis and other autoimmune diseases.

Perhaps the strongest evidence for benefits of proteolytic enzyme supplements come from numerous European studies showing various enzyme blends to be effective in accelerating recovery from exercise and injury in sportsmen as well as tissue repair in patients following surgery.




Serrapeptase supplement benefit and side effects, dosage, safety.
by Ray Sahelian, M.D.
http://www.raysahelian.com/serrapeptase.html

Serrapeptase or Serratiopeptidase, an enzyme isolated from a microorganism in silkworm, is widely used in clinical practice in Japan. ...

Serrapeptase or serratiopeptidase, isolated from the microorganism Serratia E15, is naturally present in the silkworm intestine which allows the emerging moth to dissolve its cocoon. Clinical use of serrapeptase in Europe and Asia spans over twenty five years. ...

Serrapeptase side effects - caution
A review of the medical literature indicates rare cases of pneumonitis or allergic skin reactions with the use of serrapeptase. As with any supplement or medicine, rare cases of other side effects are possible. Over the past 3 years we have had four individuals who have mentioned side effects, and these were minor aches and pains after taking serrapeptase daily for a few weeks. For this reason, we suggest limiting to one serrapeptase tablet a day and taking at least 2 days off each week until we find out whether these cases were just coincidence or true side effects from serrapeptase. ..




Serrapeptase for chronic lung disease and mucus
Effect of the proteolytic enzyme serrapeptase in patients with chronic airway disease.
Respirology. 2003 Sep;8(3):316-20.

The proteolytic enzyme serrapeptase is widely used in clinical practice in Japan. We investigated the effect of serrapeptase on sputum properties and symptoms in patients with chronic airway diseases. This study was an open-labeled trial with a non-treatment control group. Patients were randomly assigned to oral treatment and without serrapeptase 30 mg/day for 4 weeks. ...

After 4 weeks of serrapeptase treatment, sputum weight in the morning, percentage solid component, viscosity and elasticity of sputum, sputum neutrophil count, frequency of coughing and frequency of expectoration significantly decreased. Serrapeptase may exert a beneficial effect on mucus clearance by reducing neutrophil numbers and altering the viscoelasticity of sputum in patients with chronic airway diseases.



Serrapeptase for jaw pain and swelling after dental surgery.
Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus
after surgical extraction of mandibular third molars.
Int J Oral Maxillofac Surg. 2008 Mar;37(3):264-8.
Al-Khateeb TH, Nusair Y.
Division of Oral & Maxillofacial Surgery, Faculty of Dentistry, Jordan University of Science and Technology and King Abdulla University Hospital, Irbid, Jordan.

We investigated the ability of serrapeptase enzyme to reduce postoperative swelling, pain and trismus after third molar surgery. Twenty-four healthy individuals with symmetrically impacted mandibular third molars underwent surgical removal in a prospective, intra-individual, randomized, double-blind, cross-over study. Teeth were removed in 2 sessions by the same surgeon. At each session, one third molar was removed under local anaesthesia via a buccal osteotomy.

All patients received a combination of either serrapeptase 5mg or placebo tablets and 1000 mg paracetamol tablets at either the 1st or 2nd operation in accordance with the randomization plan. There was a significant reduction in the extent of cheek swelling and pain intensity in the serrapeptase group at the 2nd, 3rd and 7th postoperative days, but no significant difference in mean maximal interincisal distance was found between the 2 groups.




Serrapeptase or Serratiopeptidase research update
The effect of proteolytic enzyme serratiopeptidase in
the treatment of experimental implant-related infection.
J Bone Joint Surg Am. 2006 June.
Animal Research Laboratory, Marmara University School of Medicine, Istanbul, Turkey.

Infection around an implanted orthopedic device is a devastating complication, and the treatment of infections involving slime-forming bacteria is especially difficult. The purpose of the present study was to evaluate the effectiveness of a proteolytic enzyme, serratiopeptidase, in the eradication of a periprosthetic infection in an in vivo animal model. ... One group received serratiopeptidase enzyme injections into the knee joint in addition to antibiotic therapy for four weeks, and the other group received intra-articular saline solution injections together with the same antibiotic therapy.

Serratiopeptidase was effective for eradicating infection caused by biofilm-forming bacteria in this experimental animal model. The antibiofilm property of the enzyme may enhance antibiotic efficacy in the treatment of staphylococcal infections.




Reduction of postoperative swelling.
Objective measurement of swelling of the upper ankle joint
in treatment with serrapeptase -- a prospective study
Fortschr Med. 1989 Feb 10;107(4):67-8, 71-2.

Using a quantitative standardized procedure, the swelling of the ankle produced by supination trauma was measured. In the 66 patients with fresh rupture of the lateral ligament treated surgically at our Department between December 1986 and April 1987, a prospective study of the effect of serrapeptase (Aniflazym) on post-operative swelling and pain was carried out in 3 randomized groups of patients.

Q. Greetings from Cambridge, England, and many thanks for helpful observations on your website. It may be useful if I responsibly recount my serendipitous experience of serrapeptase. Around two years back a colleague suggested I try a few low-power daily capsules to see whether sharp big-toe joint pain might be alleviated. Gout it resembled but gout it was NOT, as my general practitioner doctor discovered to his puzzlement when the standard uric acid lab test came back negative--nonetheless, stomach-irritating anti-inflams were offered with commiserations.

I opted to try serrapeptase pills instead and found that the inflammation subsided quickly and with no stomach discomfort. Good! An unexpected side-effect, however, was that dead-tissue collagen growths in my hands (bi-lateral Dupuytren's contractures) began to itch and tingle, and over the next couple of weeks finger dexterity loosened up noticeably. Something was happening.

Background info: Two senior UK hand-surgeons, one of them US qualified, had advised against excision and z-plasty in my case as growths were judged aggressive and advanced, likely to recur within five years of surgery. I was encouraged to await availability of Santyl collagenase injection therapy (undergoing phase 3 trials and FDA control at Stoneybrook, Detroit, and elsewhere). 'Delay surgery as long as possible! Try and wait', said the surgeons. (And Phase 3 is not yet done.)

Bent ring fingers have straightened up considerably as a result of my taking enteric coated serrapeptase, 30,000 iu each day over the last two years. The growths are visibly and palpably retreating, and I can now press my palms flat on a table top. Maybe the cords will wither away or snap and dissolve as I nowadays flex fingers to degrees which were impossible before.

Presumably my lymph system is perforce processing a lot of dissolved dead tissue, unhealthy material, and this may well be a debilitating strain on the body's daily attempts to achieve homeostasis. I imagine that rises in temperature and occasional flu-like symptoms might be triggered when my body needs to rid itself of unwanted solutions. General practitioners seem puzzled and skeptical. They say nothing. A very senior hospital specialist treating chronic pain knows the enzyme and its use in state regulated medicine in Germany and Japan (for fibroids, blocked arteries, etc.), and has no reservations whatever about my using serrapeptase. I realise that this does not add up to longterm controlled trials and verifiable findings. ...



Different misspellings that have been seen for serrapeptase include serapeptase and sierrapeptase




Each Serrapeptase Rx VCap contains 300mg of enteric coated serratia peptidase enzyme preparation (PEPTIZYME SP EN) providing 30,000 I.U. of activity, which digests non-living tissue, blood clots, cysts, arterial plaque and inflammation in all forms. The late German physician, Dr. Hans Nieper, used Serrapeptase to treat arterial blockage in his coronary patients. Serrapeptase protects against stroke and is reportedly more effective and quicker than EDTA chelation treatments in removing arterial plaque. He also reports that serrapeptase dissolves blood clots and causes varicose veins to shrink or diminish. ...
http://www.aviva.ca/shop/products.asp?itemid=2301&catid=75

Serrapeptase
... (commonly misspelled as serapeptase) is an enzyme that is produced in the intestines of silk worms to break down cocoon walls. This enzyme is proving to be a superior alternative to NSAIDs (Non Steroidal Anti-Inflammatory Drugs) traditionally used to treat rheumatoid arthritis and osteoarthritis.

Serrapeptase has been used to treat chronic sinusitis, carpal tunnel syndrome, sprains and torn ligaments, fibrocystic breast disease, ovarian cysts, ear, nose and throat infections, fibromyalgia, varicose veins, emphysema, asthma, bronchitis, migraines (vascular), Inflammatory Bowel Diseases (IBD) including Crohn's, colitis and cystitis, enlarged prostate, pain, and postoperative inflammation. Some researchers believe Serrapeptase can play an important role in arterial plaque (hardening of the arteries) prevention and removal. ...

Unlike over-the-counter NSAIDs (Ibuprofen, Acetaminophen, and salicylates (Aspirin)), Serrapeptase has not been shown to cause ulcers and stomach bleeding. In fact, Serrapeptase, like many natural health products, produces numerous "side benefits." In over 25 years of use and in published studies, no side effects have been found.

Inflammation:
Our bodies have a love-hate relationship with inflammation.
On the one hand, inflammation is a natural response necessary to protect the body from invading organisms. On the other hand, excessive inflammation can limit joint function, and destroy bone, cartilage and other articular (joint) structures.

Pain Reduction:
While Serrapeptase reduces inflammation, one of its most profound benefits is reduction of pain, due to its ability to block the release of pain-inducing amines from inflamed tissues. Physicians throughout Europe and Asia have recognized the anti-inflammatory and pain-blocking benefits of this naturally occurring substance and are using it in treatment as an alternative to NSAIDs.

Post Operative Swelling and Pain:
In Germany and other European countries, Serrapeptase is a common treatment for inflammatory and traumatic swellings. One double-blind study was conducted by German researchers to determine the effect of Serrapeptase on post-operative swelling and pain. This study involved sixty-six patients who were treated surgically for fresh rupture of the lateral collateral ligament of the knee. On the third post-operative day, the group receiving Serrapeptase exhibited a 50 percent reduction of swelling, compared to the controls. The patients receiving Serrapeptase also became pain-free more rapidly than the controls, and by the tenth day, the pain had disappeared completely.

Fibro-Cystic Breast Disease:
Serrapeptase has been used in the successful treatment of fibrocystic breast disease. In a double-blind study, Serrapeptase was superior to the placebo for improvement of breast pain, breast swelling and induration (firmness). 85.7 percent of the patients receiving Serrapeptase reported moderate to marked improvement. No adverse reactions to Serrapeptase were reported. Researchers concluded that Serrapeptase is a safe and effective method for the treatment of breast engorgement.

Serrapeptase and Sinusitis:
Due to its anti-inflammatory properties, Serrapeptase has been shown in clinical studies to benefit chronic sinusitis sufferers. In this condition, the mucus in patients' nasal cavities is thickened and hypersecreted. This thickening causes mucus to be expelled less frequently. Japanese researchers evaluated the effects of Serrapeptase (30 mg/day orally for four weeks) on the elasticity and viscosity of the nasal mucus in adult patients with chronic sinusitis. Serrapeptase reduced the viscosity of the mucus, improving the elimination of bronchopulmonary secretions.

Ear, Nose and Throat, etc:
Other clinical trials support Serrapeptase's ability to relieve the problems associated with ear, nose, and throat infection, anosmia (loss of smell), nasal obstruction, laryngitis, difficulty in swallowing, often in just 3-4 days. Physicians assessed efficacy of treatment as excellent or good for 97.3 percent of patients treated with Serrapeptase compared with only 21.9 percent of those treated with a placebo. One anecdotal report indicated that Serrapeptase ended years of snoring literally overnight.

Cardiovascular Implications:
Fibrinolytic (Clot Busting) Action: Hans A. Nieper, M.D., an internist from Hannover, Germany, studied the effects of Serrapeptase on plaque accumulations in the arteries. The formation of plaque involves deposits of fatty substances, cholesterol, cellular waste products, calcium and fibrin (a clotting material in the blood) on the inner lining of the arteries. Excessive plaque results in partial or complete blockage of the blood's flow through an artery, resulting in arteriosclerosis, and potentially a stroke or heart attack. The evidence to support Serrapeptase's role in preventing plaque build-up is anecdotal. Still, further studies are called for in this area as Nieper's research indicated that the protein-dissolving action of Serrapeptase will gradually break down atherosclerotic plaques.

According to Dr. Nieper, 30,000 I.U. of Serrapetase per day for 12 to 18 months is sufficient to remove fibrous blockages from constricted coronary arteries, as confirmed in many of his patients by ultrasound examination.

When combined with Nattokinase, another amazing fibrinolytic enzyme, and other natural products including Omega 3 fatty acids and Terminalia Arjuna, natural health practitioners have a powerful method of improving cardiovascular health without the side effects of drugs. ...




StemDetox is the first detoxification product that contains a systemic, proteolitic enzyme ingredient (Serrapeptase). Systemic (proteolytic) enzymes can enhance detoxification and reduce inflammation and swelling, digest scar tissues, blood clots and cysts, improve varicose veins and arthritis, guard against fibrosis and improve fibrocystic breast disease, modulate the immune system, block the release of pain in inflamed tissues and even fight off viruses or turn around Type 1 diabetes . Enzymes also increase the effectiveness of other ingredients, allowing a lower dose to have superior results. This makes StemDetox highly efficient. Systemic enzymes also reduce the occasionally experienced die-off (Herxheimer reactions).

Even if a great detoxification protocol is followed, large amounts of fat soluble toxins remain in the fat cells, unless weight-loss is concurrent with detoxification. People often get sick when they loose weight because they flood their body with newly released toxins. StemDetox is the first and only product on the market that opens up fat cells while actively eliminating toxins from the body, resulting in weight-loss. ...

http://oradix.com/stemdetox-new-in-detoxification-c-72.html


Personal Comment:

I DO state that this option can be effective for many persons who have more singular or less devastating forms of ill health, including a number of cancers. CFS-ME is defined by a person acquiring any 5 or more of 13 specific acute expressions of chronic illnesses. I have experienced health improvement personally from this product, and/or, witnessed a number of other people benefiting from it.

Strengths often become weaknesses when applied to extremes or in situations where they are not relevant. Even as complexity in a reality which is singular is foolish and wasteful, simplicity in a reality of complexity is destructive and often deadly.

The information on this page may be relevant for you now, or, tomorrow, or, later, or, never. Consider that it will be relevant for friends and/or relatives and that YOUR mention of it to them provides them with an opportunity for them to decide for themselves if it is something they wish to consider, or, if they also would like to share it with others. YOU can make a positive difference in the world of tomorrow.

Advisory:

Always remember, just because anything is on paper or in print, there is no one forcing you to read it or believe it. Neither does it have any authority over you in the context of asserting that it is factual, the truth, or relevant for YOU. God gave you a brain with the capacity of discernment and CHOICE. Learn to use it so that you can be the director of YOUR life and the author of YOUR biography. What is on these pages is an invitation to Open some doors and consider some options for the strengthening of YOUR life and the Recovery, or, sustaining of YOUR health. It is YOUR choice what you do with it.

This document is a personal record being shared with you as an introduction to health recovery from multiple acute symptom chronic illnesses. For more complete information which may be relevant for you personally, follow the links to those pages most relevant for you, or look further on the Internet.

This is a personal recommendation based upon successful experience.
This option I have found to be beneficial for myself and others.
You have the benefit of utilizing it as early as you become aware of it.
I did not have such a Toolbag. I muddled and searched my way through until Recovery.

I have since gone back, and with Spiritual Guidance, made a format out of the pieces.
Some tools and benefits I defined AFTER Recovery in order to SUSTAIN recovery.
Many people who have Recovered from CFS-ME cannot revisit the illness experience without sacrificing their recovery. With the help of Spiritual Forces and a supportive partner, I did that in order to outline and provide this and other tools for YOUR Recovery, and to sustain my own. Make it worth the effort. I am.

Always be sure to muscle test or use Spiritual Guidance to determine if it is applicable to you, or for someone else from whom you have the permission to ask for, at the time of your interest. Serrapeptase is available in strengths up to 120,000 units per capsule. I found it best for myself, to take 4 or 5 capsules (120,000 units) at a time of this strength, often in pulsed doses. I DID have the side effect of some brain fog during the following 18 hours as the junk cleared from my system. YOUR best dosage may be radically different, and less.

Note that muscle testing can be subverted by strong and immature identity factors (Ego or SuperEgo, or, both). Note that some options are best for us at some times or in a sequence with other skills, attitudes, therapies or products, rather than at all times. Some, are simply beneficial for gaining and maintaining optimal health.

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Towards health and happiness for ALL.



We change Reality with our awareness, beliefs, perceptions, responses, and reactions. Alive, we contribute either benefits or losses to the future for ourselves and the universe. God gave you Choice.
A Gift denied is an expression of rejection and hate.
A Gift respected is a gift used wisely.


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